Antidysrhythmic Drug Therapy for the Termination of Stable, Monomorphic, Ventricular Tachycardia: A Systemic Review

deSouza IS, Martindale JL, Sinert R.  Antidysrhythmic drug therapy for the termination of stable, monomorphic ventricular tachycardia: a systemic review. Emerg Med J. 2015;32(2):161-167. doi:10.1136/emermed-2013-202973

In this systematic literature review, the authors compared the efficacy of different drug therapies for the termination of stable, monomorphic ventricular tachycardia (VT).  The literature search yielded a total of 609 articles, of which 5 studies were reviewed.  Per the authors, all reviewed studies had quality issues.  Based on limited available evidence, for the treatment of stable, monomorphic VT, procainamide, ajmaline and sotalol were all superior to lidocaine; amiodarone was not more effective than procainamide. https://pubmed.ncbi.nlm.nih.gov/24042252/