Antiarrhythmic Drug Dosing Methods, Medical Devices, and Systems

Patent No. US 11,610,660 B1

Determining the appropriate dosing of antiarrhythmic drugs can be complex, difficult to understand or apply, and/or time consuming. In situations where a patient is having a cardiovascular crisis, practitioners need to act quickly and, thus, make decisions quickly. Dosing an antiarrhythmic drug, however, often involves simultaneous and careful consideration of a plethora of parameters. The disclosure relates to a method which includes i) prompting input of: a creatinine clearance (CrCl) of a subject; whether the subject is being initiated or escalated on sotalol hydrochloride; an amount of an oral target dosage of sotalol hydrochloride for the subject; and optionally a projected start time for sotalol hydrochloride infusion; and ii) executing computer executable instructions to derive from a set of rules a sotalol hydrochloride dosing protocol for the subject based on the inputs. The disclosure also relates to systems and medical devices configured to perform one or more steps of the method, as well as a non-transitory computer-readable storage medium comprising computer-executable instructions or software stored thereon capable of performing one or more steps of the method.